Drums were banned owing to Africans' use of them for signaling, although slaves continued to be permitted string and other instruments. In , the city's 11, inhabitants—half slaves—made it the 4th-largest port after Boston , New York. Many slaves were sold from here. From , many were sold from the newly constructed Gadsden's Wharf , where six slave ships at a time could tie up. At the foundation of the town, the principal items of commerce were pine timber and pitch for ships and tobacco. At the same time, Indians were used to enslave one another.
Early immigrants to the city included Protestant French , Scottish, Irish, and Germans, as well as hundreds of Jews , predominately Sephardi from England and the Netherlands. Census, the metropolitan statistical area had a total population of , people. On December 7, , the Lords Proprietors decided to separate the Province of North Carolina from Charles Town's government, although they continued to own and control both regions. Although it did not have the high fatalities of yellow fever, it caused much illness and was also a major health problem through most of the city's history before dying out in the s after use of pesticides. The white community had recently been decimated by a malaria outbreak and the rebels killed about 25 white people before being stopped by the colonial militia; the rebellion resulted in whites killing 35 to 50 black people. Charles Town was besieged by the pirate " Blackbeard " for several days in May ; his pirates plundered merchant ships and seized the passengers and crew of the Crowley. As of the U. History[ edit ] The Pink House , the oldest stone building in Charleston, was built of Bermudian limestone at 17 Chalmers Street, between and Main articles: The British Crown did not approve the one attempt to do so in the s. Michael, now also includes parts of St. Charleston , Berkeley , and Dorchester. When the city of Charleston was formed, it was defined by the limits of the Parish of St. Charles Town suffered between 5 and 8 major yellow fever outbreaks over the first half of the 18th century. Within three years, British subsidies and high demand had already made it a leading export. The Charlestonians initially allied with the Westo , a slaving northern tribe that had grown powerful trading for guns with the colonists in Virginia. At the foundation of the town, the principal items of commerce were pine timber and pitch for ships and tobacco. From , many were sold from the newly constructed Gadsden's Wharf , where six slave ships at a time could tie up. The new town was the 5th-largest in North America by Andrew's Parish, and St. It developed a deserved reputation as one of the least healthy locations in British North America for whites, although mistaken observations over the period led some doctors to think that blacks had a natural immunity to the disease. Both Spain and France contested England's claims to the region. Rainbow Row 's 13 houses along East Bay Street formed the commercial center of the town from the colonial period through the early 20th century. Charlestown was a center for inland colonization of South Carolina , but remained the southernmost point of English settlement on the American mainland until the Province of Georgia was established in In , the city's 11, inhabitants—half slaves—made it the 4th-largest port after Boston , New York. The plantations and the economy based on them made this the wealthiest city in British North America  and the largest in population south of Philadelphia. These settlers established Charles Town at Albemarle Point on the west bank of the Ashley River a few miles northwest of the present-day city center. At the same time, Indians were used to enslave one another.
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